Alginate as an Efficacious Treatment for GERD Patients: A Literature Review

Authors

  • Ninda Septia Yuspar Universitas Sriwijaya, Palembang, Indonesia
  • Suyata Universitas Sriwijaya, Palembang, Indonesia

DOI:

https://doi.org/10.56260/sciena.v4i2.201

Keywords:

Alginate, GERD, reflux

Abstract

Gastroesophageal reflux disease (GERD) is a medical condition defined by the retrograde flow of gastric contents into the esophagus, leading to various symptoms.  The principal therapy for GERD consists of proton pump inhibitors (PPIs).  Nevertheless, PPIs demonstrate reduced effectiveness in patients with non-erosive GERD or unusual symptoms.  Alginates operate by forming a gel "raft" that floats on the gastric contents, serving as a physical barrier against reflux.  Multiple studies demonstrate that alginate is more effective than antacids in alleviating GERD symptoms and has a longer duration of action.

Author Biographies

Ninda Septia Yuspar, Universitas Sriwijaya, Palembang, Indonesia

Trainee Subspecialist Gastroenterohepatology, Department of Internal Medicine, Faculty of Medicine

Suyata, Universitas Sriwijaya, Palembang, Indonesia

Divission of Gastroenterohepatology, Department of Internal Medicine, Faculty of Medicine

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Published

2025-03-03

How to Cite

Yuspar, N. S. ., & Suyata. (2025). Alginate as an Efficacious Treatment for GERD Patients: A Literature Review. Scientific Journal, 4(2), 76–84. https://doi.org/10.56260/sciena.v4i2.201

Issue

Section

Systematic Literature Review